"There are still some incidents (in Mali] since this week there were two wounded among the French special forces," Le Drian said, without giving details of the clashes in which the injuries took place.
But, he insisted, that the country is largely pacified, while adding that "we have to be extremely vigilant about sporadic elements".
French troops have found caches of "tons" of arms, which show "considerable organisation aiming to endanger security in France and in Europe, according to Le Drian.
A horde of about 30 weapons, including machine-guns, 5,000 bullets and pick-up trucks was found in the Bourem region, the defence ministry announced on Thursday.
The 3,500-3,600 French troops in Mali at the moment will be reduced to about 2,000 as planned by the end of summer, Le Drian said, and 1,000, devoted to anti-terrorism and coordination with the UN's planned force by the end of the year, Le Drian said.