The factory, near the town of Signes on the southern coast, produces concentrates for drinks.
The shipment of 370 kilos of cocaine was hidden in a shipping container.
Workers at the factory immediately informed the police.
The Marseille prosecutor’s office said in a statement that thy have launched an investigation into the trafficking and importation of illegal drugs after the discovery.
The drugs were hidden in specially prepared sacks and are estimated to have a street value of €50 million euro.
No arrests have been made yet in relation to the haul.
This is not the first major cocaine haul made by French police. In 2015, police in Martinique seized 2.2 tonnes of cocaine in a yacht off the coast.
Coca leaves were reportedly used in the original Coca-Cola drink in the 19th century, although the company says cocaine has never been an "added ingredient."